Product nameBisindolylmaleimide VIII acetate, PKC inhibitor
DescriptionPotent, selective protein kinase C (PKC) inhibitor.
- 3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Acetic Acid Salt
- BIM VIII
- Bis VIII
Potent, selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC). Facilitates Fas-mediated apoptosis through a protein kinase C-independent mechanism and inhibits T cell-mediated autoimmune diseases.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab143782 has not yet been referenced specifically in any publications.