Overview

  • Product name

  • Description

    Rabbit polyclonal to BIT1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Macaque monkey, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide within Human BIT1 aa 129-179. The exact sequence is proprietary.
    Database link: Q9Y3E5

  • Positive control

    • WB: HeLa, HEK-293T and Jurkat cell lysate.
  • General notes

     This product was previously labelled as PTRH2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab226472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 19 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
      Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
    • Sequence similarities

      Belongs to the PTH2 family.
    • Cellular localization

      Mitochondrion.
    • Information by UniProt
    • Database links

    • Alternative names

      • Bcl 2 inhibitor of transcription 1 antibody
      • Bcl-2 inhibitor of transcription 1 antibody
      • BIT 1 antibody
      • BIT1 antibody
      • CGI 147 antibody
      • CGI147 antibody
      • mitochondrial antibody
      • Peptidyl tRNA hydrolase 2 mitochondrial antibody
      • Peptidyl-tRNA hydrolase 2 antibody
      • PTH 2 antibody
      • PTH2 antibody
      • PTH2_HUMAN antibody
      • PTRH 2 antibody
      • PTRH2 antibody
      see all

    Images

    • All lanes : Anti-BIT1 antibody (ab226472) at 0.1 µg/ml

      Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate
      Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
      Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 19 kDa


      Exposure time: 3 minutes

    References

    ab226472 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab226472.
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