Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6205] to Blood Group Antigen Precursor
- Suitable for: WB, IP
- Reacts with: Mouse, Rat, Human
Product nameAnti-Blood Group Antigen Precursor antibody [EPR6205]
See all Blood Group Antigen Precursor primary antibodies
DescriptionRabbit monoclonal [EPR6205] to Blood Group Antigen Precursor
Tested applicationsSuitable for: WB, IPmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human Blood Group Antigen Precursor (N terminal). The exact sequence is proprietary.
- Human fetal lung lysate, fetal kidney and 293T lysates.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab126612 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 41 kDa.|
|IP||1/10 - 1/100.|
FunctionThis protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
PathwayProtein modification; protein glycosylation.
Sequence similaritiesBelongs to the glycosyltransferase 6 family.
DomainThe conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
modificationsThe soluble form derives from the membrane form by proteolytic processing.
Cellular localizationGolgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
- Information by UniProt
- A transferase antibody
- A3GALNT antibody
- A3GALT1 antibody
All lanes : Anti-Blood Group Antigen Precursor antibody [EPR6205] (ab126612) at 1/1000 dilution
Lane 1 : Human fetal lung lysate
Lane 2 : 293T lysate
Lane 3 : Human fetal kidney lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat Anti-rabbit HRP at 1/2000 dilution
Predicted band size: 41 kDa
ab126612 has not yet been referenced specifically in any publications.