Overview

  • Product name

  • Description

    Goat polyclonal to BMP7
  • Host species

    Goat
  • Specificity

    ab223228 is expected to recognize precursor only.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Pig
    Predicted to work with: Mouse, Rat, Cow, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to Human BMP7 aa 120-131 (internal sequence) (Cysteine residue). NP_001710.1.
    Sequence:

    C-SLQDSHFLTDAD


    Database link: P18075

  • Positive control

    • WB: Pig kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab223228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 50-55 kDa (predicted molecular weight: 49 kDa).

Target

  • Function

    Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
  • Tissue specificity

    Expressed in the kidney and bladder. Lower levels seen in the brain.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Developmental stage

    Expressed in the developing eye, brain and ear during embryogenesis.
  • Post-translational
    modifications

    Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • BMP 7 antibody
    • BMP-7 antibody
    • Bmp7 antibody
    • BMP7_HUMAN antibody
    • Bone morphogenetic protein 7 antibody
    • Bone morphogenic protein 7 antibody
    • Eptotermin alfa antibody
    • OP 1 antibody
    • OP-1 antibody
    • OP1 antibody
    • Osteogenic protein 1 antibody
    see all

Images

  • Anti-BMP7 antibody (ab223228) at 1 µg/ml + Pig kidney lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 49 kDa
    Observed band size: 50-55 kDa
    why is the actual band size different from the predicted?



    Primary incubation was 1 hour.

References

ab223228 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab223228.
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