Overview

  • Product name

    Anti-BMP9 antibody [MM0616-16S11]
    See all BMP9 primary antibodies
  • Description

    Mouse monoclonal [MM0616-16S11] to BMP9
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Neutralisingmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Purified recombinant Human BMP9

Properties

Applications

Our Abpromise guarantee covers the use of ab135152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.
Neutralising Use at an assay dependent dilution.

Target

  • Relevance

    BMP9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. They are regulators of cell growth and differentiation. BMP9 has a role in the maturation of BFCN (basal forebrain cholinergic neurons) also inducing and maintaining the ability of these cells to respond to acetylcholine; BFCN are important for the processes of learning, memory and attention. BMP9 is a potent inducer of hepcidin (a cationic peptide that has a antimicrobial properties) in hepatocytes and can regulate iron metabolism. The physiological receptor of BMP9 is thought to be activin receptor-like kinase 1, ALK1 (also called ACVRL1), an endothelial-specific type I receptor of the TGF-beta receptor family. BMP9 is one of the most potent BMPs to induce orthotopic bone formation in vivo. BMP3, a blocker of most BMPs seems not to affect BMP9.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • BMP 9 antibody
    • Bone morphogenetic protein 9 antibody
    • GDF 2 antibody
    • GDF2 antibody
    • growth differentiation factor 2 antibody
    • Growth/differentiation factor 2 antibody
    • HHT5 antibody
    see all

References

ab135152 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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