Key features and details
- Rabbit polyclonal to BNIP3L/NIX
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-BNIP3L/NIX antibody
See all BNIP3L/NIX primary antibodies
DescriptionRabbit polyclonal to BNIP3L/NIX
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human BNIP3L/NIX aa 50-150 (internal sequence). The exact sequence is proprietary.
Database link: O60238
- K562 cells or breast carcinoma tissue.
This product is FOR RESEARCH USE ONLY. For commercial use, please contact email@example.com.
This product was previously labelled as BNIP3L
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab53185 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
1/100 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
FunctionInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
Sequence similaritiesBelongs to the NIP3 family.
modificationsUndergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
Cellular localizationNucleus envelope. Endoplasmic reticulum. Mitochondrion. Membrane.
- Information by UniProt
- Adenovirus E1B19k binding protein B5 antibody
- Adenovirus E1B19K-binding protein B5 antibody
- BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab53185 has not yet been referenced specifically in any publications.