Recombinant
RabMAb

Recombinant Anti-BNIP3L/NIX antibody [EPR4033] - BSA and Azide free (ab239976)

Overview

  • Product name

    Anti-BNIP3L/NIX antibody [EPR4033] - BSA and Azide free
    See all BNIP3L/NIX primary antibodies
  • Description

    Rabbit monoclonal [EPR4033] to BNIP3L/NIX - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human BNIP3L/NIX aa 200-300 (C terminal). The exact sequence is proprietary.

  • General notes

    ab239976 is the carrier-free version of ab109414 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab239976 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    This product was previously labelled as BNIP3L

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab239976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.

Antigen retrieval is recommended.

 

WB Use at an assay dependent concentration. Detects a band of approximately 35 kDa (predicted molecular weight: 24 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
    • Sequence similarities

      Belongs to the NIP3 family.
    • Post-translational
      modifications

      Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
    • Cellular localization

      Nucleus envelope. Endoplasmic reticulum. Mitochondrion. Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • Adenovirus E1B19k binding protein B5 antibody
      • Adenovirus E1B19K-binding protein B5 antibody
      • BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody
      • BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody
      • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody
      • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody
      • BCL2/adenovirus E1B 19kDa interacting protein 3 like antibody
      • BNI3L_HUMAN antibody
      • BNIP3a antibody
      • BNIP3H antibody
      • BNIP3L antibody
      • BNIP3L protein antibody
      • NIP3 like protein X antibody
      • NIP3-like protein X antibody
      • NIP3L antibody
      • NIX antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 1/100 ab109414

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab109414).

    References

    ab239976 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab239976.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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