Key features and details
- Rabbit polyclonal to BNP/ProBNP - C-terminal
- Suitable for: ICC, WB, ELISA, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-BNP/ProBNP antibody - C-terminal
DescriptionRabbit polyclonal to BNP/ProBNP - C-terminal
Tested applicationsSuitable for: ICC, WB, ELISA, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Non human primates
Synthetic peptide corresponding to Human BNP/ProBNP (C terminal).
Database link: P16860
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituents: 1.21% Tris, 0.75% Glycine
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab196343 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||1/200 - 1/1000.|
|WB||1/500 - 1/2000. Predicted molecular weight: 15 kDa.|
|ELISA||Use at an assay dependent concentration.|
|ICC/IF||1/200 - 1/1000.|
FunctionCardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Tissue specificityBrain and also in atria, but at much lower levels than ANP.
Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsThe brain natriuretic peptide 32 form is cleaved at Pro-104 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
- Information by UniProt
- ANFB_HUMAN antibody
- BNP antibody
- BNP(1-32) antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab196343 has not yet been referenced specifically in any publications.