Key features and details
- Irreversible general caspase inhibitor. Cell-permeable.
- CAS Number: 187389-53-3
- Soluble in DMSO to 20 mM
- Form / State: Solid
- Source: Synthetic
Product nameBoc-D-FMK, caspase inhibitor
DescriptionIrreversible general caspase inhibitor. Cell-permeable.
Irreversible general caspase inhibitor. Blocks hepatocyte apoptosis in vivo. Active in vitro and in vivo. Cell-permeable.
Chemical nameBoc-Asp(OMe)-fluoromethyl ketone
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 20 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142036 has been referenced in 1 publication.
- Qiu X et al. CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells. Cell Death Dis 6:e1864 (2015). PubMed: 26313915