Overview

  • Product name

    Anti-Bombesin antibody
  • Description

    Rabbit polyclonal to Bombesin
  • Host species

    Rabbit
  • Specificity

    Absorption with Bombesin at 10-100µg/ml of diluted antiserum abolishes the staining.
  • Tested applications

    Suitable for: IHC-Fr, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Chicken, Human
  • Immunogen

    Full length protein corresponding to Bombesin conjugated to Bovine Serum Albumin (BSA). Amphibian

  • Positive control

    • Rat or Chicken stomach

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: Whole serum
  • Purity

    Whole antiserum
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/400 - 1/800.
IHC-P 1/400 - 1/800.

Target

  • Relevance

    Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. It has two known homologues in mammals called neuromedin B and gastrin releasing peptide. It works on the gastrointestinal tract neuroendocrine hormone and it stimulates gastrin release from G cells. It activates three different G-protein coupled receptors known as BBR1 2 & 3. It also activates these receptors in the brain. Together with cholecystokinin it is the second major source of negative feedback signals that stop eating behaviour. There are three different isoforms.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • BN antibody
    • Gastric releasing peptide antibody
    • Gastrin releasing peptide antibody
    • GRP 10 antibody
    • GRP antibody
    • GRP10 antibody
    • Neuromedin C antibody
    • NeuromedinC antibody
    • Pre progastrin releasing peptide antibody
    • PreproGRP antibody
    • ProGRP antibody
    see all

References

This product has been referenced in:

  • Singh SP  et al. HIF-1a Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS One 10:e0137757 (2015). IHC-P, WB ; Mouse . Read more (PubMed: 26361040) »
See 1 Publication for this product

Customer reviews and Q&As

Question
Answer

Thank you for your phone call.
The database entry for the mouse NFkB protein is as follows:
http://www.uniprot.org/uniprot/Q04207
There, you will find the list of potential phosporylation sites, their kinases as well as references.

Please see below for the testing discount code for ab86037 for use in mouse:
DISCOUNT CODE: xxx
Expiration date: xxx
I am very pleased to hear you would like to accept our offer and test ab86037 in mouse. This code will give you 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please submit an Abreview for mouse and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.
Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.
Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.
The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.

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