Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
Key features and details
- Rabbit polyclonal to Bone marrow stromal cell antigen 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Bone marrow stromal cell antigen 1 antibody
See all Bone marrow stromal cell antigen 1 primary antibodies -
Description
Rabbit polyclonal to Bone marrow stromal cell antigen 1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-146 of Human Bone marrow stromal cell antigen 1.
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Positive control
- 293T, H1299, Molt-4, and Raji cell lysates; Human W480 xenograft.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab137718 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 36 kDa. | |
| IHC-P | 1/100 - 1/1000. Perform heat mediated antigen retrieval using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) before commencing with IHC staining protocol. |
Target
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Function
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. -
Tissue specificity
Widely expressed. -
Sequence similarities
Belongs to the ADP-ribosyl cyclase family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 683 Human
- Omim: 600387 Human
- SwissProt: Q10588 Human
- Unigene: 720344 Human
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Alternative names
- ADP ribosyl cyclase 2 antibody
- ADP-ribosyl cyclase 2 antibody
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 antibody
see all
Images
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Western blot - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)Anti-Bone marrow stromal cell antigen 1 antibody (ab137718) at 1/500 dilution + Raji whole cell lysate at 30 µg
Predicted band size: 36 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)Immunohistochemical analysis of paraffin-embedded SW480 xenograft labelling Bone marrow stromal cell antigen 1 with ab137718 at 1/100 dilution.
Protocols
References (2)
ab137718 has been referenced in 2 publications.
- Yang Q et al. CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production. mBio 10:N/A (2019). PubMed: 31455656
- Ceroni F et al. A deletion involving CD38 and BST1 results in a fusion transcript in a patient with autism and asthma. Autism Res 7:254-63 (2014). PubMed: 24634087
