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Immunology Adaptive Immunity B Cells CD
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Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)

  • Datasheet
  • SDS
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Western blot - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)

Key features and details

  • Rabbit polyclonal to Bone marrow stromal cell antigen 1
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

You may also be interested in

Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-Bone marrow stromal cell antigen 1 antibody
    See all Bone marrow stromal cell antigen 1 primary antibodies
  • Description

    Rabbit polyclonal to Bone marrow stromal cell antigen 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-146 of Human Bone marrow stromal cell antigen 1.

  • Positive control

    • 293T, H1299, Molt-4, and Raji cell lysates; Human W480 xenograft.
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Immunology
    • Adaptive Immunity
    • B Cells
    • CD
    • Signal Transduction
    • Signaling Pathway
    • Calcium Signaling
    • Other
    • Immunology
    • Immune System Diseases
    • Autoimmune
    • Immunology
    • Innate Immunity
    • Myeloid Cells

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Positive Controls

    • Raji whole cell lysate (ab30124)
    • MOLT4 whole cell lysate (ab7912)
  • Recombinant Protein

    • Recombinant Human Bone marrow stromal cell antigen 1 protein (His tag) (ab235881)

Applications

Our Abpromise guarantee covers the use of ab137718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 36 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) before commencing with IHC staining protocol.

Target

  • Function

    Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Belongs to the ADP-ribosyl cyclase family.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession Q10588 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 683 Human
    • Omim: 600387 Human
    • SwissProt: Q10588 Human
    • Unigene: 720344 Human
    • Alternative names

      • ADP ribosyl cyclase 2 antibody
      • ADP-ribosyl cyclase 2 antibody
      • ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 antibody
      • Bone marrow stromal antigen 1 antibody
      • Bone marrow stromal cell antigen 1 antibody
      • BST 1 antibody
      • BST-1 antibody
      • BST1 antibody
      • BST1_HUMAN antibody
      • cADPr hydrolase 2 antibody
      • CD157 antibody
      • CD157 antigen antibody
      • Cyclic ADP ribose hydrolase 2 antibody
      • Cyclic ADP-ribose hydrolase 2 antibody
      • NAD(+) nucleosidase antibody
      • OTTHUMP00000217617 antibody
      see all

    Images

    • Western blot - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
      Western blot - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
      Anti-Bone marrow stromal cell antigen 1 antibody (ab137718) at 1/500 dilution + Raji whole cell lysate at 30 µg

      Predicted band size: 36 kDa



      10% SDS PAGE
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bone marrow stromal cell antigen 1 antibody (ab137718)
      Immunohistochemical analysis of paraffin-embedded SW480 xenograft labelling Bone marrow stromal cell antigen 1 with ab137718 at 1/100 dilution.

    Protocols

    • Western blot protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (2)

    Publishing research using ab137718? Please let us know so that we can cite the reference in this datasheet.

    ab137718 has been referenced in 2 publications.

    • Yang Q  et al. CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production. mBio 10:N/A (2019). PubMed: 31455656
    • Ceroni F  et al. A deletion involving CD38 and BST1 results in a fusion transcript in a patient with autism and asthma. Autism Res 7:254-63 (2014). PubMed: 24634087

    Customer reviews and Q&As

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