Anti-BOTOX antibody (ab20641)
Key features and details
- Rabbit polyclonal to BOTOX
- Suitable for: ELISA, WB
- Reacts with: Species independent
- Isotype: IgG
Overview
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Product name
Anti-BOTOX antibody
See all BOTOX primary antibodies -
Description
Rabbit polyclonal to BOTOX -
Host species
Rabbit -
Specificity
Clostridium botulinum Type A Neurotoxin. -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Species independent -
Immunogen
Full length protein corresponding to BOTOX.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Constituents: 2.68% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20641 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA |
1/10000.
|
|
| WB | (1) |
Use at an assay dependent dilution. Predicted molecular weight: 149 kDa.
|
| Notes |
|---|
|
ELISA
1/10000. |
|
WB
Use at an assay dependent dilution. Predicted molecular weight: 149 kDa. |
Target
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Relevance
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25. -
Alternative names
- Atx antibody
- BotA antibody
- BOTOX antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab20641 has been referenced in 4 publications.
- Bagramyan K et al. Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples. Anal Chem 85:5569-76 (2013). PubMed: 23656526
- Scotcher MC et al. Epitope characterization and variable region sequence of f1-40, a high-affinity monoclonal antibody to botulinum neurotoxin type a (Hall strain). PLoS ONE 4:e4924 (2009). WB . PubMed: 19290051
- Scotcher MC et al. Characterization of the epitope region of F1-2 and F1-5, two monoclonal antibodies to Botulinum neurotoxin type A. Hybridoma (Larchmt) 28:315-25 (2009). WB . PubMed: 19857112
- Bagramyan K et al. Attomolar detection of botulinum toxin type A in complex biological matrices. PLoS ONE 3:e2041 (2008). PubMed: 18446228