Overview

  • Product name

    bpV(phen), PTP and PTEN inhibitor
  • Description

    Potent, broad spectrum PTP and PTEN inhibitor. Insulin receptor kinase activator.
  • Biological description

    Potent, broad spectrum PTP and PTEN inhibitor (IC50 = 38 nM, PTEN). Insulin mimetic. Activates insulin receptor kinase. Prevents ketonuria in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    42494-73-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Suo ZW  et al. Inhibition of protein tyrosine phosphatases in spinal dorsal horn attenuated inflammatory pain by repressing Src signaling. Neuropharmacology 70:122-30 (2013). Read more (PubMed: 23376245) »
  • Becker L  et al. Ex vivo neurogenesis within enteric ganglia occurs in a PTEN dependent manner. PLoS One 8:e59452 (2013). Read more (PubMed: 23527198) »
  • Band CJ  et al. Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen). Mol Endocrinol 11:1899-910 (1997). Read more (PubMed: 9415395) »

Customer reviews and Q&As

Answer


Yes I can confirm that up to 10 mM is completely dissolvable in water, this is correct.

We recommend using aqueous solution of bpV(phen) immediately and not storing the material in solution. No special precautions are required when discarding unused material beyond the normal measures taken for chemicals waste.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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