Overview

  • Product name

    Anti-BRAG2 antibody - N-terminal
    See all BRAG2 primary antibodies
  • Description

    Rabbit polyclonal to BRAG2 - N-terminal
  • Host species

    Rabbit
  • Specificity

    At least four isoforms of BRAG2 are known to exist. ab211434 is predicted to not cross-react with IQSEC2.
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human BRAG2 (N terminal). The immunogen was a 19 amino acid peptide near the N terminal of Human BRAG2
    Database link: Q6DN90

  • Positive control

    • IHC-P- Human tonsil tissue, human kidney tissue.
  • General notes

    Previously labelled as IQSEC1.

Properties

Applications

Our Abpromise guarantee covers the use of ab211434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 108 kDa.

Target

  • Function

    In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.
  • Tissue specificity

    Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.
  • Sequence similarities

    Belongs to the BRAG family.
    Contains 1 IQ domain.
    Contains 1 PH domain.
    Contains 1 SEC7 domain.
  • Cellular localization

    Cytoplasm. Nucleus. At steady state, may be preferentially cytosolic.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADP-ribosylation factors guanine nucleotide-exchange protein 100 antibody
    • ADP-ribosylation factors guanine nucleotide-exchange protein 2 antibody
    • ARF GEP100 antibody
    • ARFGEP100 antibody
    • BRAG2 antibody
    • Brefeldin A resistant ARF GEF2 antibody
    • Brefeldin-resistant Arf-GEF 2 protein antibody
    • GEP100 antibody
    • IQ motif and Sec7 domain 1 antibody
    • IQ motif and SEC7 domain-containing protein 1 antibody
    • IQEC1_HUMAN antibody
    • Iqsec1 antibody
    • Kiaa0763 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue labeling BRAG2 with ab211434 at 10 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney tissue labeling BRAG2 with ab211434 at 10 µg/mL.

References

ab211434 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab211434.
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