Overview

  • Product name
    BrdU (5-bromo-2'-deoxyuridine), Thymidine analog
  • Description
    Thymidine analog for measuring cell proliferation
  • Biological description

    Thymidine analog, naturally incorporates into proliferating cells. Labels DNA, useful marker for study of DNA synthesis. Decreases TTP pools in vitro. Antitumor and radiation-sensitizing agent. Active in vitro and in vivo.

  • Purity
    > 98%
  • General notes

    Unstained control slides from mice treated with BrdU (formalin-fixed, paraffin-embedded intestine sections) are available as BrdU control slides ab129956

  • CAS Number
    59-14-3
  • Chemical structure
    Chemical Structure

Properties

Images

  • Estimation of S-phase Duration using EdU-BrdU Dual Pulse Labelling.

    (From Figure 5A of Massey)

References

This product has been referenced in:
  • Takagi S  et al. Detection of 5-bromo-2-deoxyuridine (BrdUrd) incorporation with monoclonal anti-BrdUrd antibody after deoxyribonuclease treatment. Cytometry 14:640-8 (1993). Read more (PubMed: 8404370) »
  • Shewach DS  et al. Decrease in TTP pools mediated by 5-bromo-2'-deoxyuridine exposure in a human glioblastoma cell line. Biochem Pharmacol 43:1579-85 (1992). Read more (PubMed: 1567479) »
  • Brennan LM  et al. An in vivo method for using 5-bromo-2'-deoxyuridine (BrdU) as a marker of chemically-induced hepatocellular proliferation in the Japanese medaka (Oryzias latipes). Toxicol Pathol 29:387-97 (0). Read more (PubMed: 11442025) »
See all 9 Publications for this product

Customer reviews and Q&As

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Abreviews
It works very well. The complementary protocol on the Abcam website is straightforward and easy to follow.
I used it at the concentration of 10 micromolar and left for 2 hours in culture.

Abcam user community

Verified customer

Submitted Nov 27 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"
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