Validated using a knockout cell line

Anti-BRG1 antibody [EPNCIR111A] (ab110641)

Publishing research using ab110641? Please let us know so that we can cite the reference in this datasheet.

ab110641 has been referenced in 38 publications.

  • Lino Cardenas CL  et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun 9:1009 (2018). PubMed: 29520069
  • Ito K  et al. Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes. Mol Biol Cell 29:209-219 (2018). PubMed: 29142070
  • Agaimy A  et al. SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients. Hum Pathol 77:139-146 (2018). IHC-P . PubMed: 29689242
  • Ge M  et al. Propofol post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional activation in human and mice. J Cell Mol Med 21:3693-3704 (2017). WB . PubMed: 28749008
  • Ge M  et al. Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects. Oxid Med Cell Longev 2017:8787392 (2017). PubMed: 28798861
  • Raab JR  et al. Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits. Epigenetics Chromatin 10:62 (2017). PubMed: 29273066
  • Jiang W  et al. Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma. Oncotarget 8:37423-37434 (2017). PubMed: 28445125
  • Chronis C  et al. Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell 168:442-459.e20 (2017). PubMed: 28111071
  • Su MT  et al. The SWI/SNF Chromatin Regulator, BRG1, Modulates the Transcriptional Regulatory Activity of the EBV DNA Polymerase Processivity Factor BMRF1. J Virol N/A:N/A (2017). PubMed: 28228591
  • Yoshida A  et al. Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities. Mod Pathol N/A:N/A (2017). IHC-P ; Human . PubMed: 28256572
  • Alver BH  et al. The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers. Nat Commun 8:14648 (2017). CHIPseq ; Mouse . PubMed: 28262751
  • Sauter JL  et al. SMARCA4-deficient thoracic sarcoma: a distinctive clinicopathological entity with undifferentiated rhabdoid morphology and aggressive behavior. Mod Pathol N/A:N/A (2017). IHC ; Human . PubMed: 28643792
  • Kim YH  et al. Pediatric intracerebral histiocytic sarcoma with rhabdoid features: Case report and literature review. Neuropathology N/A:N/A (2017). IHC ; Human . PubMed: 28748542
  • King HW & Klose RJ The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells. Elife 6:N/A (2017). PubMed: 28287392
  • Hou H  et al. Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A. Medicine (Baltimore) 95:e5241 (2016). PubMed: 28002318
  • Hohmann AF  et al. Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition. Nat Chem Biol 12:672-9 (2016). PubMed: 27376689
  • Jiang W  et al. Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma. PLoS One 11:e0164554 (2016). IHC-P ; Human . PubMed: 27764136
  • Agaimy A  et al. Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract. Virchows Arch 469:321-30 (2016). PubMed: 27339451
  • Coatham M  et al. Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas. Mod Pathol N/A:N/A (2016). PubMed: 27562491
  • Karnezis AN  et al. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type. J Pathol 238:389-400 (2016). IHC-P ; Human . PubMed: 26356327
  • Deng X  et al. Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth. Oncogene N/A:N/A (2016). WB, ChIP ; Human . PubMed: 27546619
  • Jamshidi F  et al. The genomic landscape of epithelioid sarcoma cell lines and tumours. J Pathol 238:63-73 (2016). IHC ; Human . PubMed: 26365879
  • Clarke BA  et al. Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics. Histopathology 69:727-738 (2016). IHC ; Human . PubMed: 27100627
  • Chowdhury B  et al. PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma. PLoS One 11:e0153718 (2016). WB ; Human . PubMed: 27100670
  • Karnezis AN  et al. Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas. Mod Pathol 29:302-14 (2016). IHC ; Human . PubMed: 26743474
  • Yoshida A  et al. Differential SALL4 immunoexpression in malignant rhabdoid tumours and epithelioid sarcomas. Histopathology 66:252-61 (2015). PubMed: 24827994
  • Alajem A  et al. Differential association of chromatin proteins identifies BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation. Cell Rep 10:2019-31 (2015). ChIP ; Mouse . PubMed: 25818293
  • Laurette P  et al. Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells. Elife 4:N/A (2015). WB ; Human . PubMed: 25803486
  • Yoshimoto T  et al. Frequent loss of the expression of multiple subunits of the SWI/SNF complex in large cell carcinoma and pleomorphic carcinoma of the lung. Pathol Int 65:595-602 (2015). IHC ; Human . PubMed: 26345631
  • Alexander JM  et al. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development 142:1418-30 (2015). ChIP ; Mouse . PubMed: 25813539
  • Stavreva DA  et al. Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing. Genome Res 25:845-57 (2015). PubMed: 25677181
  • Madsen MS  et al. Peroxisome proliferator-activated receptor ? and C/EBPa synergistically activate key metabolic adipocyte genes by assisted loading. Mol Cell Biol 34:939-54 (2014). ChIP . PubMed: 24379442
  • Ramos P  et al. Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nat Genet 46:427-9 (2014). IHC ; Human . PubMed: 24658001
  • Goljanek-Whysall K  et al. myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis. Development 141:3378-87 (2014). WB ; Mouse . PubMed: 25078649
  • Otte A  et al. In vitro and in vivo therapeutic approach for a small cell carcinoma of the ovary hypercalcaemic type using a SCCOHT-1 cellular model. Orphanet J Rare Dis 9:126 (2014). WB ; Human . PubMed: 25103190
  • Joliot V  et al. The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation. PLoS One 9:e108858 (2014). ChIP . PubMed: 25271443
  • Ramos P  et al. Loss of the tumor suppressor SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Rare Dis 2:e967148 (2014). IHC-P ; Human . PubMed: 26942101
  • Sanalkumar R  et al. Mechanism governing a stem cell-generating cis-regulatory element. Proc Natl Acad Sci U S A 111:E1091-100 (2014). ChIP . PubMed: 24616499


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