Overview

  • Product name
  • Description
    Rabbit polyclonal to BRMS1L
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 10-222 of Human BRMS1L (Q5PSV4)

  • Positive control
    • 293T whole cell lysate, paraffin-embedded HBL435 xenograft

Properties

Applications

Our Abpromise guarantee covers the use of ab155188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 38 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. use 10mM Citrate buffer or alternatively Tris-EDTA buffer (pH 8.0) may be used

Target

  • Function
    Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth.
  • Sequence similarities
    Belongs to the BRMS1 family.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • breast cancer metastasis suppressor 1 like antibody
    • Breast cancer metastasis-suppressor 1-like protein antibody
    • BRM1L_HUMAN antibody
    • BRMS1 homolog protein p40 antibody
    • BRMS1 like protein p40 antibody
    • BRMS1-homolog protein p40 antibody
    • BRMS1-like protein p40 antibody
    • BRMS1L antibody
    • FLJ39177 antibody
    see all

Images

  • Anti-BRMS1L antibody (ab155188) at 1/3000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size: 38 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded HBL435 xenograft labeling BRMS1L with ab155188 at 1/500 dilution.

References

This product has been referenced in:
  • Sardiu ME  et al. Suberoylanilide hydroxamic acid (SAHA)-induced dynamics of a human histone deacetylase protein interaction network. Mol Cell Proteomics 13:3114-25 (2014). Read more (PubMed: 25073741) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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