Overview

  • Product name
  • Description
    Rabbit polyclonal to Brn-2
  • Host species
    Rabbit
  • Specificity
    At least two isoforms are known to exist. ab139734 will recognize both isoforms. ab139734 is predicted to not cross-react with other members of the POU domain class 3 family.
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Brn-2 (C terminal).

  • Positive control
  • General notes

    Protein name formally labeled as POU3F2.

Properties

Applications

Our Abpromise guarantee covers the use of ab139734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 46 kDa.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters.
  • Tissue specificity
    Expressed specifically in the neuroectodermal cell lineage.
  • Sequence similarities
    Belongs to the POU transcription factor family. Class-3 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Brain 2 antibody
    • Brain specific homeobox/POU domain protein 2 antibody
    • Brain-2 antibody
    • Brain-specific homeobox/POU domain protein 2 antibody
    • BRN 2 antibody
    • Brn-2 antibody
    • BRN2 antibody
    • N Oct 3 antibody
    • N OCT 3 Gene antibody
    • N Oct3 antibody
    • Nervous system specific octamer binding transcription factor antibody
    • Nervous system-specific octamer-binding transcription factor N-Oct-3 antibody
    • OCT 7 antibody
    • Oct-7 antibody
    • OCT7 antibody
    • Octamer Binding Transcription Factor 7 antibody
    • Octamer-binding protein 7 antibody
    • Octamer-binding transcription factor 7 antibody
    • OTF 7 antibody
    • OTF-7 antibody
    • OTF7 antibody
    • PO3F2_HUMAN antibody
    • POU class 3 homeobox 2, antibody
    • POU domain class 3 transcription factor 2 antibody
    • POU domain, class 3, transcription factor 2 antibody
    • Pou3f2 antibody
    • POUF 3 antibody
    • POUF3 antibody
    • Protein Brn 2 antibody
    see all

Images

  • Immunofluorescence of Brn-2 in Human brain tissue with ab139734 at 20 ug/mL.

  • Lane 1 : Anti-Brn-2 antibody (ab139734) at 1 µg/ml
    Lane 2 : Anti-Brn-2 antibody (ab139734) at 2 µg/ml

    All lanes : 3T3 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 46 kDa

References

ab139734 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab139734.
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