Key features and details
- Rabbit polyclonal to BSND
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-BSND antibody
See all BSND primary antibodies
DescriptionRabbit polyclonal to BSND
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human BSND aa 54-320.
CQCYPKITFVPADSDFQGILSPKAMGLLENGLAAEMKSPSPQPPYVRLWE EAAYDQSLPDFSHIQMKVMSYSEDHRSLLAPEMGQPKLGTSDGGEGGPGD VQAWMEAAVVIHKGSDESEGERRLTQSWPGPLACPQGPAPLASFQDDLDM DSSEGSSPNASPHDREEACSPQQEPQGCRCPLDRFQDFALIDAPTLEDEP QEGQQWEIALPNNWQRYPRTKVEEKEASDTGGEEPEKEEEDLYYGLPDGA GDLLPDKELGFEPDTQG
Database link: Q8WZ55
- IHC-P: Human breast cancer and kidney tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab238741 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
FunctionFunctions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Tissue specificityExpressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
Involvement in diseaseBartter syndrome 4A
Cellular localizationCell membrane. Cytoplasm. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral.
- Information by UniProt
- BART antibody
- Bartter syndrome infantile with sensorineural deafness antibody
- Bartter syndrome, infantile, with sensorineural deafness (Barttin) antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab238741 has not yet been referenced specifically in any publications.