Key features and details
- Potent, selective Na+/2Cl-/K+ cotransporter inhibitor
- CAS Number: 28395-03-1
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameBumetanide, Na+/2Cl-/K+ cotransporter inhibitor
DescriptionPotent, selective Na+/2Cl-/K+ cotransporter inhibitor
Biological descriptionPotent, selective Na+/2Cl-/K+ cotransporter inhibitor. Shows 40-fold greater potency than furosemide (Asc 314). Shows diuretic and anticonvulsant effects in vivo. Orally active.
Chemical name3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 50 mM and in ethanol to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Ion pumps / transporter
- Na+/2Cl-/K+ cotransporter
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142489 has not yet been referenced specifically in any publications.