Overview

  • Product name

    Bupranolol, beta adrenoceptor antagonist
  • Description

    Potent non-selective β adrenoceptor antagonist
  • Biological description

    Potent non-selective β adrenoceptor antagonist (Ki values are 5.2, 50 and 170 nM at β2, β1 and β3, respectively). Similar potency to propranolol (ab120757).
  • Purity

    > 99%
  • CAS Number

    14556-46-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zelaszczyk D  et al. Four close bupranolol analogues are antagonists at the low-affinity state of beta1-adrenoceptors. J Physiol Pharmacol 60:51-60 (2009). Read more (PubMed: 19439807) »
  • Babu RJ  et al. Cardiovascular effects of transdermally delivered bupranolol in rabbits: effect of chemical penetration enhancers. Life Sci 82:273-8 (2008). Read more (PubMed: 18096189) »
  • Malinowska B  et al. Atypical cardiostimulant beta-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues. Br J Pharmacol 139:1548-54 (2003). Read more (PubMed: 12922943) »
  • Candelore MR  et al. Potent and selective human beta(3)-adrenergic receptor antagonists. J Pharmacol Exp Ther 290:649-55 (1999). Read more (PubMed: 10411574) »

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