Bupropion hydrochloride, Non-selective DAT/NET inhibitor (ab120534)
Key features and details
- Non-selective DAT/NET inhibitor
- CAS Number: 31677-93-7
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bupropion hydrochloride, Non-selective DAT/NET inhibitor -
Description
Non-selective DAT/NET inhibitor -
Biological description
Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.
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CAS Number
31677-93-7 -
Chemical structure
Properties
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Chemical name
(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride -
Molecular weight
276.20 -
Molecular formula
C13H18ClNO.HCl -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab120534 has not yet been referenced specifically in any publications.