Recombinant
RabMAb

Recombinant Anti-Butyrylcholinesterase antibody [EPR3033(2)] (ab151554)

Overview

  • Product name

    Anti-Butyrylcholinesterase antibody [EPR3033(2)]
    See all Butyrylcholinesterase primary antibodies
  • Description

    Rabbit monoclonal [EPR3033(2)] to Butyrylcholinesterase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Butyrylcholinesterase aa 550-650 (C terminal). The exact sequence is proprietary.

  • Positive control

    • A375, HeLa and 293T cell lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab151554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 68 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
    • Tissue specificity

      Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
    • Involvement in disease

      Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.
    • Sequence similarities

      Belongs to the type-B carboxylesterase/lipase family.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • Acylcholine acylhydrolase antibody
      • BCHE antibody
      • Butyrylcholine esterase antibody
      • CHE1 antibody
      • CHE2 antibody
      • CHLE_HUMAN antibody
      • Choline esterase II antibody
      • Cholinesterase (serum) 2 antibody
      • Cholinesterase 1 antibody
      • Cholinesterase antibody
      • E1 antibody
      • Pseudocholinesterase antibody
      • Pseudocholinesterase E1 antibody
      see all

    Images

    • All lanes : Anti-Butyrylcholinesterase antibody [EPR3033(2)] (ab151554) at 1/1000 dilution

      Lane 1 : A375 cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labeled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 68 kDa

    References

    ab151554 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151554.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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