Overview

  • Product name

  • Description

    Rabbit polyclonal to BVR
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rabbit, Chimpanzee, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide within Human BVR aa 75-125. The exact sequence is proprietary. NP_000703.2.
    Sequence:

    SESSSH EDYIRQFLNA GKHVLVEYPM TLSLAAAQEL WELAEQKGKV LHEEH


    Database link: P53004

  • Positive control

    • HeLa, 293T and Jurkat whole cell lysates.
  • General notes

    Protein previously labeled as Biliverdin Reductase.

Properties

Applications

Our Abpromise guarantee covers the use of ab192925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
WB 1/1000 - 1/5000. Predicted molecular weight: 33 kDa.

Target

  • Function

    Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
  • Tissue specificity

    Liver.
  • Pathway

    Porphyrin-containing compound metabolism; protoheme degradation.
  • Involvement in disease

    Hyperbiliverdinemia
  • Sequence similarities

    Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BIEA_HUMAN antibody
    • Biliverdin IX alpha reductase antibody
    • Biliverdin reductase A antibody
    • Biliverdin-IX alpha-reductase antibody
    • BLVR A antibody
    • BLVR antibody
    • Blvra antibody
    • BVR A antibody
    • BVR antibody
    • BVRA antibody
    • Zinc metalloprotein antibody
    see all

Images

  • Detection of BVR in Immunoprecipitates of 293T whole cell lysates (1 mg for IP, 20% of IP loaded) using ab192925 at 6 µg/reaction for IP and 1µg/ml for WB detection.

    Detection: Chemiluminescence with an exposure time of 3 minutes.

  • All lanes : Anti-BVR antibody (ab192925) at 0.4 µg/ml

    Lane 1 : HeLa whole cell lysate
    Lane 2 : 293T whole cell lysate
    Lane 3 : Jurkat whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 33 kDa


    Exposure time: 3 minutes

References

ab192925 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192925.
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