BVT 948, Protein tyrosine phosphatase (PTP) inhibitor (ab141304)
Key features and details
- Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor
- CAS Number: 39674-97-0
- Purity: > 99%
- Soluble in DMSO to 50 mM and in ethanol to 20 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BVT 948, Protein tyrosine phosphatase (PTP) inhibitor -
Description
Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor -
Biological description
Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC50 values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.
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Purity
> 99% -
CAS Number
39674-97-0 -
Chemical structure
Properties
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Chemical name
4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione -
Molecular weight
241.25 -
Molecular formula
C14H11NO3 -
PubChem identifier
6604934 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 20 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC=2C(=O)c1ccccc1C3=NC(=O)C(C)(C)C=23 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - BVT 948, Protein tyrosine phosphatase (PTP) inhibitor (ab141304)2D chemical structure image of ab141304, BVT 948, Protein tyrosine phosphatase (PTP) inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141304 has not yet been referenced specifically in any publications.