Key features and details
- Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor
- CAS Number: 39674-97-0
- Purity: > 99%
- Soluble in DMSO to 50 mM and in ethanol to 20 mM
- Form / State: Solid
- Source: Synthetic
Product nameBVT 948, Protein tyrosine phosphatase (PTP) inhibitor
DescriptionNon-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor
Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC50 values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.
Storage instructionsStore at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 50 mM and in ethanol to 20 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141304 has not yet been referenced specifically in any publications.