Overview

  • Product name

    Anti-C Reactive Protein antibody [C2]
    See all C Reactive Protein primary antibodies
  • Description

    Mouse monoclonal [C2] to C Reactive Protein
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-P, ELISA, Sandwich ELISA, Competitive ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Human C Reactive Protein, derived from pleural/ascetic fluid or plasma.

  • General notes

    This product was changed from ascites to tissue culture supernatant on 17th October 2017 and product received after this date will be from tissue culture supernatant.

Properties

Applications

Our Abpromise guarantee covers the use of ab136176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Sandwich ELISA Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [C6] to C Reactive Protein (HRP) (ab24462) and Mouse monoclonal [C6] to C Reactive Protein (ab8278) and Mouse monoclonal [C5] to C Reactive Protein (ab8279).

Recommended pairs for sandwich immunoassay
(capture - detection):
C2 - C6
C5 - C6
C7 - C6.

Competitive ELISA Use at an assay dependent concentration.

Target

  • Function

    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • Tissue specificity

    Found in plasma.
  • Sequence similarities

    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Pentraxin 1, short antibody
    • C reactive protein antibody
    • C reactive protein pentraxin related antibody
    • C-reactive protein(1-205) antibody
    • CRP antibody
    • CRP_HUMAN antibody
    • MGC88244 antibody
    • Pentraxin 1 antibody
    • PTX 1 antibody
    • PTX1 antibody
    see all

References

ab136176 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer


I have confirmed with the lab and most of our C Reactive Protein antibodies, except C3 and C4, react with both monomer and pentamer form of CRP. (As our clones C3 and C4 do not recognize CRP in the absence of Ca2+ ions, we suggest that they could not recognize CRP monomer, but we have never experimentally tested this.)


ab10026, Anti-C Reactive Protein antibody [C1]


ab136176, Anti-C Reactive Protein antibody [C2]


ab8279, Anti-C Reactive Protein antibody [C5]


ab24462, Anti-C Reactive Protein antibody [C6] (HRP)


As pair I can recommend ab24462 and ab8279 to recognize both, monomer and pentamer.


https://www.abcam.com/index.html?datasheet=24462 (or use the following: https://www.abcam.com/index.html?datasheet=24462).


https://www.abcam.com/index.html?datasheet=8279 (or use the following: https://www.abcam.com/index.html?datasheet=8279).

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