Overview

  • Product name
    Anti-C Reactive Protein antibody [C2] (HRP)
    See all C Reactive Protein primary antibodies
  • Description
    Mouse monoclonal [C2] to C Reactive Protein (HRP)
  • Host species
    Mouse
  • Conjugation
    HRP
  • Specificity
    Human CRP. Specific antibody titer in ELISA is > 10 to the power of -6
  • Tested applications
    Suitable for: ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab24461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution.
    sELISA: Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [C5] to C Reactive Protein (ab8279) and Mouse monoclonal [C6] to C Reactive Protein (ab8278).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
    • Tissue specificity
      Found in plasma.
    • Sequence similarities
      Belongs to the pentaxin family.
      Contains 1 pentaxin domain.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Pentraxin 1, short antibody
      • C reactive protein antibody
      • C reactive protein pentraxin related antibody
      • C-reactive protein(1-205) antibody
      • CRP antibody
      • CRP_HUMAN antibody
      • MGC88244 antibody
      • Pentraxin 1 antibody
      • PTX 1 antibody
      • PTX1 antibody
      see all

    References

    ab24461 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    1-4 of 4 Abreviews or Q&A

    Answer

    Thank you for contacting us.

    I am sorry we do not have any data to confirm how many ab molecules binds to CRP. Theoretically, I agree there is possibility of binding 5 ab molecule per pentamer of CRP however we can't be sure as we do not know for how many chains the epitope is exposed for antibody binding.

    I am sorry due to non availability of tested we will not be able to confirm this.

    I hope this information is nevertheless helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Use our products? Submit an Abreview. Earn rewards!
    https://www.abcam.com/abreviews

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    Answer

    Thank you for contacting us. Dr. Tanya is out of office today so I am dealing with her inquiries.

    The immunogen for these antibodies is a proprietary information. These antibodies are raised sing full length human CRP protein. The two products are tested positive in sandwich ELISA.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Use our products? Submit an Abreview. Earn rewards!
    https://www.abcam.com/abreviews

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    Answer

    Thank you for contacting us. My search also shows just the single biotinylated antibody, anti-rat CRP, ab86246.

    We do have biotinylation kits which are very easy to use. For instance, the rabbit polyclonal antibody ab31156 can be biotinylated with ab102863 or ab102866, depending on the intended use of the antibody. (Please see the Product Overview section of each datasheet for an explanation of the differences between the two products).

    Click here (or use the following: https://www.abcam.com/index.html?datasheet=86246).

    Click here (or use the following: https://www.abcam.com/index.html?datasheet=102863).

    Click here (or use the following: https://www.abcam.com/index.html?datasheet=102866).

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    Answer

    Thank you for contacting us.
    We do not use the terminology C number. These does not depicts any information other the clone numbers for a particular antibody.
    The sELISA pairs we recommend are
    The best pair is C2-C6 (ab24461 detection - ab8278 capture)
    C5-C6 (ab8279 capture - ab24462 detection)
    C7-C6 (ab8280 capture - ab24462 detection)
    Please ab24462 is a HRP conjugated anti C reactive protein antibody; due to the conjugation it will be a good detection antibody.
    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.
    Use our products? Submit an Abreview. Earn rewards!
    https://www.abcam.com/abreviews

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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