Anti-C Reactive Protein antibody [C5] (ab8279)
- Datasheet
- References (3)
- Protocols
Overview
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Product nameAnti-C Reactive Protein antibody [C5]
See all C Reactive Protein primary antibodies -
DescriptionMouse monoclonal [C5] to C Reactive Protein
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Host speciesMouse
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SpecificityHuman CRP Specific antibody titer in ELISA is > 10 to the power of -6
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Tested applicationsSuitable for: ELISA, Sandwich ELISAmore details
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Species reactivityReacts with: Human
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Immunogen
Full length native protein (purified) (Human).
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General notes
Detects CRP in the presence and absence of Ca2+.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Storage bufferPBS with 0.1% sodium azide, pH 7.4
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Concentration information loading...
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PurityAscites
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Purification notesPurified from ascites.
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Primary antibody notesdetects CRP in the presence and absence of Ca2+.
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ClonalityMonoclonal
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Clone numberC5
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MyelomaSp2/0
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IsotypeIgG2a
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Light chain typeunknown
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Research areas
Associated products
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Compatible Secondaries
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ELISA pair antibody
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Isotype control
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sELISA pair antibody
Applications
Our Abpromise guarantee covers the use of ab8279 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA | Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [C6] to C Reactive Protein (ab8278). Capture | |
Sandwich ELISA | Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [C6] to C Reactive Protein (HRP) (ab24462). |
Target
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FunctionDisplays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
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Tissue specificityFound in plasma.
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Sequence similaritiesBelongs to the pentaxin family.
Contains 1 pentaxin domain. -
Cellular localizationSecreted.
- Information by UniProt
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Database links
- Entrez Gene: 1401 Human
- Omim: 123260 Human
- SwissProt: P02741 Human
- Unigene: 709456 Human
- Unigene: 76452 Human
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Alternative names
- Pentraxin 1, short antibody
- C reactive protein antibody
- C reactive protein pentraxin related antibody
see all
References
This product has been referenced in:
- Verschoor CP et al. DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly. Exp Gerontol 105:47-52 (2018). Sandwich ELISA . Read more (PubMed: 29032243) »
- Verschoor CP et al. Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents. J Infect Dis 216:191-197 (2017). Read more (PubMed: 28838148) »