Overview

  • Product name

    Anti-C10 antibody - C-terminal
    See all C10 primary antibodies
  • Description

    Rabbit polyclonal to C10 - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab198183 detects endogenous level of total C10 protein.

  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Mouse C10 (C terminal). The exact sequence is proprietary. NCBI Accession No. NP_033165.
    Database link: P27784

  • Positive control

    • Human lung cancer tissue.
  • General notes

    Protein target previously labeled as CCL6.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    CCL6 (C10) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. It is a potent chemoattractant of macrophages, but it can also attract B cells, CD4+ lymphocytes and eosinophils. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be induced under conditions suitable for myeloid cell differentiation. CCL6 (C10) was originally identified as a transcript that is induced in bone marrow cells upon stimulation of GMCSF. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • C10 antibody
    • CCL 6 antibody
    • chemokine (C-C motif) ligand 6 antibody
    • Chemokine C C motif Ligand 6 antibody
    • MRP1 antibody
    • SCYA6 antibody
    • Small Inducible Cytokine A6 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling C10 using ab198183 at a 1/50 dilution.

References

ab198183 has not yet been referenced specifically in any publications.

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