C12 E8 solution, Non-ionic detergent (ab146285)

Overview

  • Product name

    C12 E8 solution, Non-ionic detergent
  • Description

    Non-ionic detergent.
  • Alternative names

    • 3,6,9,12,15,18,21,24-octaoxahexatriacontan-1-ol
    • C12E8
    • Dodecyl octaethylene glycol ether
    • Dodecyloctaglycol
    • Octaethylene glycol monododecyl ether
    • Octaethyleneglycol Mono-n-dodecyl Ether
    • Polyoxyethylene (8) lauryl ether
    see all
  • Biological description

    Non-ionic detergent used for solubilization of membrane-bound proteins in their native state. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

  • CAS Number

    3055-98-9
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    538.80
  • Molecular formula

    C28H58O9
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Supplied as a 10% (w/v) aqueous solution
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Fogeron ML  et al. Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins. Protein Expr Purif 105:39-46 (2015). Read more (PubMed: 25306874) »
  • Romero F Solubilization and partial characterization of ouabain-insensitive Na(+)-ATPase from basolateral plasma membranes of the intestinal epithelial cells. Invest Clin 50:303-14 (2009). Read more (PubMed: 19961053) »
  • Musatov A  et al. Detergent-solubilized bovine cytochrome c oxidase: dimerization depends on the amphiphilic environment. Biochemistry 39:12996-3004 (2000). Read more (PubMed: 11041865) »
  • López-Nicolás JM  et al. An octaethylene glycol monododecyl ether-based mixed micellar assay for lipoxygenase acting at neutral pH. Anal Biochem 221:410-5 (1994). Read more (PubMed: 7810887) »
  • Levy D  et al. Phospholipid vesicle solubilization and reconstitution by detergents. Symmetrical analysis of the two processes using octaethylene glycol mono-n-dodecyl ether. Biochemistry 29:9480-8 (1990). Read more (PubMed: 2248960) »
  • Stegmann T  et al. Functional reconstitution of influenza virus envelopes. EMBO J 6:2651-9 (1987). Read more (PubMed: 3678202) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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