Anti-C12orf48 antibody - C-terminal (ab211634)

Overview

  • Product name

    Anti-C12orf48 antibody - C-terminal
  • Description

    Rabbit polyclonal to C12orf48 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human C12orf48 aa 522-550 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. NP_060385.3.
    Sequence:

    CDNRNEPPQ HKNAKIPKKS NDSQNRLYGK


    Database link: Q9NWS1

  • Positive control

    • A549 cell line lysate; Human testis tissue; A549 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab211634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB 1/1000. Predicted molecular weight: 65 kDa.
Flow Cyt 1/10 - 1/50.

Target

  • Function

    May be involved in RNA metabolism. Binds single-strand DNA and poly(A) homopolymers (By similarity). Positively regulate the poly(ADP-ribosyl)ation activity of PARP1.
  • Tissue specificity

    Restricted to testis. Overexpressed in multiple cancer cells.
  • Sequence similarities

    Belongs to the PARP1BP family.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • AROM antibody
    • C12orf48 antibody
    • Chromosome 12 open reading frame 48 antibody
    • FLJ20641 antibody
    • PARP 1 binding protein antibody
    • PARP-1 binding protein antibody
    • PARP1 binding protein antibody
    • PARP1-binding protein antibody
    • PARPBP antibody
    • PR1BP_HUMAN antibody
    see all

Images

  • Anti-C12orf48 antibody - C-terminal (ab211634) at 1/1000 dilution + A549 cell line lysate at 35 µg

    Predicted band size: 65 kDa

  • Flow Cytometric analysis of A549 cells labeling C12orf48 with ab211634 at 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling C12orf48 with ab211634 at 1/50 dilution.

References

ab211634 has not yet been referenced specifically in any publications.

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