Anti-C12orf65 antibody (ab122448)
Key features and details
- Rabbit polyclonal to C12orf65
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-C12orf65 antibody -
Description
Rabbit polyclonal to C12orf65 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant antigen sequence: GLFHFPTPLT RICPAPWGLR LWEKLTLLSP GIAVTPVQMA GKKDYPALLS LDENELEEQF VKGHGPGGQA TNKTSNC, corresponding to amino acids 5-81 of Human C12orf65
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Positive control
- WB: SCLC-21H cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122448 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.04 - 0.4 µg/ml.
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Notes |
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WB
Use a concentration of 0.04 - 0.4 µg/ml. |
Target
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Function
May act as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion. -
Involvement in disease
Defects in C12orf65 are the cause of combined oxidative phosphorylation deficiency type 7 (COXPD7) [MIM:613559]. A mitochondrial disease resulting in encephalomyopathy. Clinical manifestations include psychomotor delay and regression, ataxia, optic atrophy, nystagmus and muscle atrophy and weakness. -
Sequence similarities
Belongs to the prokaryotic/mitochondrial release factor family. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 91574 Human
- Omim: 613541 Human
- SwissProt: Q9H3J6 Human
- Unigene: 319128 Human
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Alternative names
- C12orf65 antibody
- chromosome 12 open reading frame 65 antibody
- CL065_HUMAN antibody
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Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab122448 has not yet been referenced specifically in any publications.