Key features and details
- Rabbit polyclonal to C1r
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-C1r antibody
See all C1r primary antibodies
DescriptionRabbit polyclonal to C1r
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Cow, Non human primates
Synthetic peptide corresponding to Human C1r aa 50-150 conjugated to keyhole limpet haemocyanin.
(Peptide available as
- Recombinant Human C1r protein (ab116915) can be used as a positive control in WB. This antibody gave a positive signal in Human Plasma (Total Protein)
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab71652 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionC1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Sequence similaritiesBelongs to the peptidase S1 family.
Contains 2 CUB domains.
Contains 1 EGF-like domain.
Contains 1 peptidase S1 domain.
Contains 2 Sushi (CCP/SCR) domains.
modificationsThe iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
- Information by UniProt
- C1 R antibody
- C1R antibody
- C1R_HUMAN antibody
All lanes : Anti-C1r antibody (ab71652) at 1 µg/ml
Lane 1 : Human Plasma Total Protein Lysate at 2 µg
Lane 2 : Human Plasma Total Protein Lysate at 5 µg
Lane 3 : Human Plasma Total Protein Lysate at 10 µg
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 80 kDa
Observed band size: 80 kDa
Additional bands at: 90 kDa (possible glycosylated form)
Exposure time: 1 minute
ab71652 has been referenced in 2 publications.
- Gröbner R et al. C1R Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome. Front Immunol 10:2537 (2019). WB ; Human . PubMed: 31749804
- Takiya CS et al. Proteomic analysis reveals greater abundance of complement and inflammatory proteins in subcutaneous adipose tissue from postpartum cows treated with sodium salicylate. J Proteomics 204:103399 (2019). PubMed: 31152939