Overview

  • Product name

    Anti-C1RL antibody
  • Description

    Rabbit polyclonal to C1RL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 190-239 of Human C1RL (NP_057630).

  • Positive control

    • Human Fetal Liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab136685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa.

Target

  • Function

    Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
  • Tissue specificity

    Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).
  • Sequence similarities

    Belongs to the peptidase S1 family.
    Contains 1 CUB domain.
    Contains 1 peptidase S1 domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C1r like protein antibody
    • C1r like serine protease analog antibody
    • C1r like serine protease analog protein antibody
    • C1r LP antibody
    • C1r-like protein antibody
    • C1r-like serine protease analog protein antibody
    • C1r-LP antibody
    • C1rl antibody
    • C1RL_HUMAN antibody
    • C1RL1 antibody
    • C1RLP antibody
    • CLSPa antibody
    • complement C1r like proteinase antibody
    • Complement C1r subcomponent-like protein antibody
    • Complement component 1 r subcomponent like antibody
    see all

Images

  • Anti-C1RL antibody (ab136685) at 1 µg/ml + Human Fetal Liver lysate at 10 µg

    Predicted band size: 53 kDa

References

ab136685 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab136685.
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