Anti-C3 antibody [11H9] (ab11862)

Rat monoclonal C3 antibody [11H9]. Validated in WB, IP, ELISA, IHC, Flow Cyt, ICC/IF and tested in Mouse. Cited in 20 publication(s). Independently reviewed in 2 review(s).

Publishing research using ab11862? Please let us know so that we can cite the reference in this datasheet.

ab11862 has been referenced in 23 publications.

  • Ugarte-Berzal E  et al. MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus. Front Immunol 10:538 (2019). PubMed: 30967870
  • Illouz T  et al. Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model. Brain Behav Immun 75:163-180 (2019). PubMed: 30389461
  • Zhao Y  et al. High glucose-induced complement component 3 up-regulation via RAGE-p38MAPK-NF-?B signalling in astrocytes: In vivo and in vitro studies. J Cell Mol Med 22:6087-6098 (2018). PubMed: 30246940
  • Wang X  et al. Inhibition of microRNA-182-5p contributes to attenuation of lupus nephritis via Foxo1 signaling. Exp Cell Res 373:91-98 (2018). PubMed: 30308195
  • Inoue MK  et al. The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model. Int J Mol Sci 19:N/A (2018). PubMed: 30544662
  • Xiong C  et al. Complement activation contributes to perioperative neurocognitive disorders in mice. J Neuroinflammation 15:254 (2018). PubMed: 30180861
  • Zhao M  et al. IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation. Nat Commun 9:583 (2018). IHC . PubMed: 29422534
  • Huang B  et al. Non-erythropoietic erythropoietin-derived peptide protects mice from systemic lupus erythematosus. J Cell Mol Med 22:3330-3339 (2018). PubMed: 29570934
  • Harder JM  et al. Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective. Proc Natl Acad Sci U S A 114:E3839-E3848 (2017). PubMed: 28446616
  • Toffoli B  et al. Nephropathy in Pparg-null mice highlights PPAR? systemic activities in metabolism and in the immune system. PLoS One 12:e0171474 (2017). IHC-P ; Mouse . PubMed: 28182703
  • Haure-Mirande JV  et al. Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology. Acta Neuropathol N/A:N/A (2017). PubMed: 28612290
  • Li GS  et al. Complement components of nerve regeneration conditioned fluid influence the microenvironment of nerve regeneration. Neural Regen Res 11:682-6 (2016). WB . PubMed: 27212935
  • Zhu J  et al. Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE2 production. Am J Physiol Renal Physiol 310:F895-908 (2016). PubMed: 26887830
  • Lui H  et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell 165:921-35 (2016). WB, Flow Cyt ; Mouse . PubMed: 27114033
  • Murayama MA  et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun 6:8483 (2015). Mouse . PubMed: 26404464
  • Sweigard JH  et al. Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury. Sci Transl Med 7:297ra116 (2015). PubMed: 26203084
  • Schraivogel D  et al. Importin-ß facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res 43:7447-61 (2015). PubMed: 26170235
  • Hou S  et al. Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol N/A:N/A (2014). Mouse . PubMed: 24399151
  • Garland DL  et al. Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration. Hum Mol Genet N/A:N/A (2013). PubMed: 23943789
  • Hirano M  et al. Role of interaction of mannan-binding protein with meprins at the initial step of complement activation in ischemia/reperfusion injury to mouse kidney. Glycobiology 22:84-95 (2012). IHC-P ; Mouse . PubMed: 21835783
  • Chiu IM  et al. Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice. Proc Natl Acad Sci U S A 106:20960-5 (2009). IHC-FoFr ; Mouse . PubMed: 19933335
  • Rodino-Klapac LR  et al. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. Neurology 71:240-7 (2008). Mouse . PubMed: 18525034
  • Kovacs A  et al. Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia. Proc Natl Acad Sci U S A 104:13768-73 (2007). IHC-Fr ; Mouse . PubMed: 17702862

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