Anti-C3a R antibody (ab126250)

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Overview

  • Product name

    Anti-C3a R antibody
    See all C3a R primary antibodies

  • Description

    Rabbit polyclonal to C3a R

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Non human primates, Macaque monkey, Orangutan

  • Immunogen

    Recombinant fragment corresponding to Human C3a R aa 1-209.

  • Positive control

    • A549 whole cell lysate

  • General notes

    Previously labelled as C3a Receptor.

Properties

Applications

Our Abpromise guarantee covers the use of ab126250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 54 kDa. Optimal working dilutions should be determined experimentally by the user
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

  • Tissue specificity

    Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Post-translational
    modifications

    Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • AZ 3B antibody
      • AZ3B antibody
      • C3a anaphylatoxin chemotactic receptor antibody
      • C3A R antibody
      • C3A R1 antibody
      • C3a Receptor antibody
      • C3a-R antibody
      • C3AR antibody
      • C3AR_HUMAN antibody
      • C3AR1 antibody
      • C3R1 antibody
      • Complement component 3 receptor 1 antibody
      • Complement component 3a receptor 1 antibody
      • HNFAG09 antibody
      see all

    Images

    • Western blot - Anti-C3a R antibody (ab126250)
      Western blot - Anti-C3a R antibody (ab126250)
      Anti-C3a R antibody (ab126250) at 1/3000 dilution + A549 whole cell lysate at 30 µg

      Predicted band size: 54 kDa



      10% SDS-PAGE
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3a R antibody (ab126250)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3a R antibody (ab126250)
      ab126250, at 1/500 dilution, staining paraffin-embedded colon ca by immunohistochemical analysis

    References

    This product has been referenced in:

    See all 2 Publications for this product

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