Overview

  • Product name

  • Description

    Rabbit polyclonal to C3a R
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except ADRA1A (40%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human C3a R.
    Database link: NP_004045.1

  • Positive control

    • Human lung (respiratory epithelium) tissue, Human small intestine.
  • General notes

    Previously labelled as C3a Receptor.

Properties

Applications

Our Abpromise guarantee covers the use of ab140788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 17.3 µg/ml.

Target

  • Function

    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
  • Tissue specificity

    Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • AZ 3B antibody
    • AZ3B antibody
    • C3a anaphylatoxin chemotactic receptor antibody
    • C3A R antibody
    • C3A R1 antibody
    • C3a Receptor antibody
    • C3a-R antibody
    • C3AR antibody
    • C3AR_HUMAN antibody
    • C3AR1 antibody
    • C3R1 antibody
    • Complement component 3 receptor 1 antibody
    • Complement component 3a receptor 1 antibody
    • HNFAG09 antibody
    see all

Images

  • Immunohistochemical analysis of Human lung tissue labelling C3a R with ab140788 at 17.3 µg/ml.

  • Immunohistochemical analysis of Human small intestine tissue labelling C3a R with ab140788 at 17.3 µg/ml.

References

ab140788 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140788.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up