Key features and details
- Rabbit polyclonal to C4BPA
- Suitable for: IHC-P, WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-C4BPA antibody
See all C4BPA primary antibodies
DescriptionRabbit polyclonal to C4BPA
Tested applicationsSuitable for: IHC-P, WB, ICC/IFmore details
Species reactivityReacts with: Human
- Human small intestine tissue; Human Liver and Human Tonsil lysates
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab121123 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
|ICC/IF||Use a concentration of 1 - 4 µg/ml.|
FunctionControls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Tissue specificityChylomicrons in the plasma.
Sequence similaritiesContains 8 Sushi (CCP/SCR) domains.
- Information by UniProt
- C4b-binding protein alpha chain antibody
- C4bp antibody
- C4bpa antibody
All lanes : Anti-C4BPA antibody (ab121123) at 1/250 dilution
Lane 1 : RT4 cell lysate
Lane 2 : U-251 MG cell lysate
Lane 3 : A431 cell lysate
Lane 4 : Human Liver lysate
Lane 5 : Human Tonsil lysate
Developed using the ECL technique.
10-20% SDS PAGE
ab121123 at 1/475 dilution staining C4BPA in Paraffin-emebedded Human small intestine tissue by Immunohistochemistry. Note: distinct positivity in plasma.
ab121123 has not yet been referenced specifically in any publications.