Anti-C5a-R antibody [W17/1] (ab11884)
Key features and details
- Mouse monoclonal [W17/1] to C5a-R
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-C5a-R antibody [W17/1]
See all C5a-R primary antibodies -
Description
Mouse monoclonal [W17/1] to C5a-R -
Host species
Mouse -
Species reactivity
Reacts with: Human -
Immunogen
This information is considered to be commercially sensitive.
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General notes
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
W17/1 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Target
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Function
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Post-translational
modificationsSulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 728 Human
- Omim: 113995 Human
- SwissProt: P21730 Human
- Unigene: 2161 Human
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Alternative names
- ANAPHYLATOXIN RECEPTOR antibody
- C5a anaphylatoxin chemotactic receptor antibody
- C5a anaphylatoxin receptor antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab11884 has been referenced in 2 publications.
- Chung SI et al. IL-13 is a therapeutic target in radiation lung injury. Sci Rep 6:39714 (2016). PubMed: 28004808
- Yuan J et al. C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Arthritis Res Ther 14:R140 (2012). PubMed: 22691190