Anti-C5b-9 antibody (ab55811)

Rabbit polyclonal C5b-9 antibody. Validated in IHC, RID, ICC/IF and tested in Mouse, Human. Cited in 35 publication(s). Independently reviewed in 2 review(s).

Publishing research using ab55811? Please let us know so that we can cite the reference in this datasheet.

ab55811 has been referenced in 42 publications.

  • Fang L  et al. Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG. Neurosci Bull N/A:N/A (2019). PubMed: 31041694
  • Zhu X  et al. All-trans retinoic acid protects mesenchymal stem cells from immune thrombocytopenia by regulating the complement-IL-1ß loop. Haematologica N/A:N/A (2019). PubMed: 30679324
  • Duan T  et al. Complement-independent bystander injury in AQP4-IgG seropositive neuromyelitis optica produced by antibody-dependent cellular cytotoxicity. Acta Neuropathol Commun 7:112 (2019). PubMed: 31296268
  • Merle NS  et al. Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles. JCI Insight 3:N/A (2018). PubMed: 29925688
  • Wang B  et al. Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia-reperfusion. Mol Med Rep 18:4523-4529 (2018). PubMed: 30221740
  • Jeon H  et al. Activation of the complement system in an osteosarcoma cell line promotes angiogenesis through enhanced production of growth factors. Sci Rep 8:5415 (2018). ELISA, ICC/IF . PubMed: 29615744
  • Tougan T  et al. Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5. Sci Rep 8:5052 (2018). PubMed: 29567995
  • Gallenkamp J  et al. A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma. Oncotarget 9:3001-3013 (2018). PubMed: 29423024
  • Hu C  et al. Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling. J Immunol 201:3717-3730 (2018). PubMed: 30429287
  • Olcina MM  et al. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Rep 25:3721-3732.e6 (2018). PubMed: 30590044
  • Granados-Durán P  et al. Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation. Front Neurol 8:78 (2017). PubMed: 28326060
  • Jeon H  et al. Extracellular vesicles from KSHV-infected endothelial cells activate the complement system. Oncotarget 8:99841-99860 (2017). ICC/IF ; Human . PubMed: 29245944
  • Berg CT  et al. Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination. J Neuroinflammation 14:127 (2017). IHC-P ; Mouse . PubMed: 28646890
  • Doberentz E & Madea B Microscopic examination of pituitary glands in cases of fatal accidental hypothermia. Forensic Sci Res 2:132-138 (2017). PubMed: 30483631
  • Granados-Durán P  et al. Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. J Neuroinflammation 13:115 (2016). IHC . PubMed: 27209022
  • Chen J  et al. C5b-9 Staining Correlates With Clinical and Tumor Stage in Gastric Adenocarcinoma. Appl Immunohistochem Mol Morphol 24:470-5 (2016). IHC-P ; Human . PubMed: 26186252
  • Marneros AG Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms. EMBO Mol Med 8:208-31 (2016). PubMed: 26912740
  • Manenti L  et al. Association of Serum C3 Concentration and Histologic Signs of Thrombotic Microangiopathy with Outcomes among Patients with ANCA-Associated Renal Vasculitis. Clin J Am Soc Nephrol 10:2143-51 (2015). PubMed: 26542163
  • Murayama MA  et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun 6:8483 (2015). PubMed: 26404464
  • Jiang M  et al. Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. J Cell Biol 210:595-611 (2015). IHC-P ; Mouse . PubMed: 26261180
  • Song M  et al. Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. Cell Metab 21:273-85 (2015). PubMed: 25600785
  • Planagumà J  et al. Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice. Brain 138:94-109 (2015). PubMed: 25392198
  • Chen T  et al. Chronic progressive external ophthalmoplegia with inflammatory myopathy. Int J Clin Exp Pathol 7:8887-92 (2014). IHC-Fr ; Human . PubMed: 25674260
  • Chen C  et al. Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injury. J Am Heart Assoc 3:e000683 (2014). IHC-Fr ; Mouse . PubMed: 24390148
  • Tong HH  et al. Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice. PLoS One 9:e95160 (2014). IHC-P ; Mouse . PubMed: 24740152
  • Ferrer MF  et al. Decay-accelerating factor 1 deficiency exacerbates leptospiral-induced murine chronic nephritis and renal fibrosis. PLoS One 9:e102860 (2014). IHC-P ; Mouse . PubMed: 25032961
  • Mayer F  et al. Dityrosine, a protein product of oxidative stress, as a possible marker of acute myocardial infarctions. Int J Legal Med 128:787-94 (2014). PubMed: 24819153
  • Lee MS  et al. Exploitation of the complement system by oncogenic Kaposi's sarcoma-associated herpesvirus for cell survival and persistent infection. PLoS Pathog 10:e1004412 (2014). IHC-P ; Human . PubMed: 25254972
  • de Bock L  et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol 193:2147-56 (2014). PubMed: 25086173
  • Ioannou A  et al. Complement depletion protects lupus-prone mice from ischemia-reperfusion-initiated organ injury. Am J Physiol Gastrointest Liver Physiol 304:G283-92 (2013). Mouse . PubMed: 23104558
  • Papareddy P  et al. The TFPI-2 derived peptide EDC34 improves outcome of gram-negative sepsis. PLoS Pathog 9:e1003803 (2013). WB ; Human . PubMed: 24339780
  • Olaru F  et al. Neonatal Fc Receptor Promotes Immune Complex-Mediated Glomerular Disease. J Am Soc Nephrol N/A:N/A (2013). Mouse . PubMed: 24357670
  • Kim CH  et al. Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors. Leukemia 26:106-16 (2012). PubMed: 21769103
  • Zhang JJ  et al. Murine membranous nephropathy: immunization with a3(IV) collagen fragment induces subepithelial immune complexes and Fc?R-independent nephrotic syndrome. J Immunol 188:3268-77 (2012). ICC/IF ; Mouse . PubMed: 22371398
  • Geis C  et al. Human stiff-person syndrome IgG induces anxious behavior in rats. PLoS One 6:e16775 (2011). IHC-Fr ; Rat . PubMed: 21346811
  • Xu H  et al. Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion. Invest Ophthalmol Vis Sci 52:249-55 (2011). IHC-Fr ; Mouse . PubMed: 20720227
  • Tezel G  et al. Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci 51:5071-82 (2010). IHC-P ; Human . PubMed: 20484586
  • Saadoun S  et al. Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain 133:349-61 (2010). ICC/IF ; Mouse . PubMed: 20047900
  • Chen Y  et al. Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci U S A 107:9035-42 (2010). ICC/IF ; Mouse . PubMed: 20418503
  • Fujimoto K  et al. Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A 107:10214-9 (2010). IHC-P ; Mouse . PubMed: 20479245
  • Ratajczak MZ  et al. Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex. Leukemia 24:976-85 (2010). IHC-P ; Mouse . PubMed: 20357827
  • Lundh von Leithner P  et al. Complement factor h is critical in the maintenance of retinal perfusion. Am J Pathol 175:412-21 (2009). IHC-FoFr ; Mouse . PubMed: 19541934

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