Overview

  • Product name

    C6-NBD-ceramide, fluorescent sphingosine analog
  • Description

    Fluorescent C6:0-sphingosine analog
  • Alternative names

    • C6-NBD-ceramide
    • N-Hexanoyl-NBD-D-erythro-sphingosine
  • Biological description

    Fluorescent C6:0-sphingosine analog. For use in CERT trafficking studies and as internal standard. Possible activity in vitro.

    See similar compounds

  • Purity

    > 98%
  • CAS Number

    86701-10-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(E,2S,3R)-1,3-Dihydroxyoctadec-4-en-2-yl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide
  • Molecular weight

    575.74
  • Molecular formula

    C30H49N5O6
  • PubChem identifier

    16219783
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Hullin-Matsuda F  et al. Limonoid compounds inhibit sphingomyelin biosynthesis by preventing CERT protein-dependent extraction of ceramides from the endoplasmic reticulum. J Biol Chem 287:24397-411 (2012). Read more (PubMed: 22605339) »
  • Kudo N  et al. Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide. Proc Natl Acad Sci U S A 105:488-93 (2008). Read more (PubMed: 18184806) »
  • Hanada K  et al. Molecular machinery for non-vesicular trafficking of ceramide. Nature 426:803-9 (2003). Read more (PubMed: 14685229) »
See 1 Publication for this product

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