• Product name

    Anti-C7 antibody [EPR7036]
    See all C7 primary antibodies
  • Description

    Rabbit monoclonal [EPR7036] to C7
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, Flow Cyt, ICC/IFmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human C7 aa 800-900. The exact sequence is proprietary.
    Database link: P10643

  • Positive control

    • HepG2, Ramos, K562 and HUVEC cell lysates; Human kidney tissue; HepG2 cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.


  • Form

  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

  • Clone number

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab126786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 94 kDa (predicted molecular weight: 94 kDa).
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.
    • Involvement in disease

      Defects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
    • Sequence similarities

      Belongs to the complement C6/C7/C8/C9 family.
      Contains 1 EGF-like domain.
      Contains 1 LDL-receptor class A domain.
      Contains 1 MACPF domain.
      Contains 2 Sushi (CCP/SCR) domains.
      Contains 2 TSP type-1 domains.
    • Post-translational

      C7 has 28 disulfide bridges.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • C7 antibody
      • CO7_HUMAN antibody
      • complement component 7 antibody
      • Complement component C7 antibody


    • All lanes : Anti-C7 antibody [EPR7036] (ab126786) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : HUVEC cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 94 kDa

    • ab126786, at a 1/250 dilution, staining C7 in paraffin embedded Human kidney tissue by Immunohistochemistry.

      Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    • ab126786, at a 1/100 dilution, staining C7 in HepG2 cells by Immunofluorescence.


    This product has been referenced in:

    • Tougan T  et al. Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5. Sci Rep 8:5052 (2018). Read more (PubMed: 29567995) »
    • Li GS  et al. Complement components of nerve regeneration conditioned fluid influence the microenvironment of nerve regeneration. Neural Regen Res 11:682-6 (2016). WB . Read more (PubMed: 27212935) »
    See all 2 Publications for this product

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