Overview

  • Product name

    C75, fatty acid synthase (FAS) inhibitor
  • Description

    Competitive, irreversible fatty acid synthase (FAS) inhibitor
  • Biological description

    Competitive, irreversible fatty acid synthase (FAS) inhibitor (IC50 = 200 μM). Suppresses expression of neuropeptide Y and agouti-related protein. Antitumor and anti-obesity agent. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    191282-48-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Pellinen J & Szentirmai É The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice. PLoS One 7:e30651 (2012). Read more (PubMed: 22348016) »
  • Rendina AR & Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. Biochem J 388:895-903 (2005). Read more (PubMed: 15715522) »
  • Hu Z  et al. Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects. Proc Natl Acad Sci U S A 102:3972-7 (2005). Read more (PubMed: 15728730) »

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