Anti-CAB3 antibody (ab16717)

Reviews (1) Submit a question References (1)

Key features and details

  • Rabbit polyclonal to CAB3
  • Reacts with: Rat
  • Isotype: IgG

Overview

  • Product name

    Anti-CAB3 antibody

  • Description

    Rabbit polyclonal to CAB3

  • Host species

    Rabbit

  • Specificity

    This antibody recognises the beta 3 calcium channel subunit.

  • Species reactivity

    Reacts with: Rat

  • Immunogen

    Synthetic peptide corresponding to CAB3 aa 1-15 conjugated to keyhole limpet haemocyanin.
    Sequence:

    MYDDSYVPGFEDSEA

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells

  • General notes

    Protein previously labeled as CACNB3.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.40
    Preservative: 0.08% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Ammonium Sulphate Precipitation

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Target

  • Function

    The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

  • Tissue specificity

    Expressed mostly in brain, smooth muscle and ovary.

  • Sequence similarities

    Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Information by UniProt

  • Database links

    • Alternative names

      • CAB3 antibody
      • CACB3_HUMAN antibody
      • Cacnb3 antibody
      • CACNLB3 antibody
      • Calcium channel voltage dependent beta 3 subunit antibody
      • Calcium channel voltage-dependent subunit beta 3 antibody
      • FLJ58949 antibody
      • Voltage-dependent L-type calcium channel subunit beta-3 antibody
      see all

    References (1)

    Publishing research using ab16717? Please let us know so that we can cite the reference in this datasheet.

    ab16717 has been referenced in 1 publication.

    • Uriu Y  et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . PubMed: 20452978

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Western blot abreview for Anti-CAB3 antibody

     Good
    Abreviews
    abreview image
    Application
    Western blot
    Sample
    Rat Recombinant protein (recombinant protein from e.Coli)
    Gel Running Conditions
    Reduced Denaturing
    Loading amount
    10 µg
    Specification
    recombinant protein from e.Coli
    Blocking step
    Milk as blocking agent for 15 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
    Read More

    Abcam user community

    Verified customer

    Submitted Oct 23 2008

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com