Anti-CAB3 antibody (ab16717)
Key features and details
- Rabbit polyclonal to CAB3
- Suitable for: IP, ICC/IF, WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-CAB3 antibody -
Description
Rabbit polyclonal to CAB3 -
Host species
Rabbit -
Specificity
This antibody recognises the beta 3 calcium channel subunit. -
Tested applications
Suitable for: IP, ICC/IF, WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide corresponding to CAB3 aa 1-15 conjugated to keyhole limpet haemocyanin.
Sequence:MYDDSYVPGFEDSEA
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Positive control
- Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Ammonium Sulphate Precipitation -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab16717 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IP |
Use at an assay dependent concentration.
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| ICC/IF |
Use at an assay dependent concentration.
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| WB | (1) |
Use at an assay dependent concentration.
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| Notes |
|---|
|
IP
Use at an assay dependent concentration. |
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ICC/IF
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
Target
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Function
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. -
Tissue specificity
Expressed mostly in brain, smooth muscle and ovary. -
Sequence similarities
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain. - Information by UniProt
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Database links
- Entrez Gene: 25297 Rat
- SwissProt: P54287 Rat
- Unigene: 2808 Rat
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Alternative names
- CAB3 antibody
- CACB3_HUMAN antibody
- Cacnb3 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab16717 has been referenced in 1 publication.
- Uriu Y et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . PubMed: 20452978
