Key features and details
- Rabbit polyclonal to CAB3
- Suitable for: WB, IP, ICC/IF
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-CAB3 antibody
DescriptionRabbit polyclonal to CAB3
SpecificityThis antibody recognises the beta 3 calcium channel subunit.
Tested applicationsSuitable for: WB, IP, ICC/IFmore details
Species reactivityReacts with: Rat
- Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells
Protein previously labeled as CACNB3.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.08% Sodium azide
Concentration information loading...
PurityAmmonium Sulphate Precipitation
Our Abpromise guarantee covers the use of ab16717 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 58 kDa.|
|IP||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution.|
FunctionThe beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Tissue specificityExpressed mostly in brain, smooth muscle and ovary.
Sequence similaritiesBelongs to the calcium channel beta subunit family.
Contains 1 SH3 domain.
- Information by UniProt
- CAB3 antibody
- CACB3_HUMAN antibody
- Cacnb3 antibody
ab16717 has been referenced in 1 publication.
- Uriu Y et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . PubMed: 20452978