Anti-CAB3 antibody (ab16717)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-CAB3 antibody
See all CAB3 primary antibodies -
DescriptionRabbit polyclonal to CAB3
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Host speciesRabbit
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SpecificityThis antibody recognises the beta 3 calcium channel subunit.
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Tested applicationsSuitable for: WB, IP, ICC/IFmore details
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Species reactivityReacts with: Rat
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Immunogen
Synthetic peptide corresponding to CAB3 aa 1-15 conjugated to keyhole limpet haemocyanin.
Sequence:MYDDSYVPGFEDSEA
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Positive control
- Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells
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General notes
Protein previously labeled as CACNB3.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.08% Sodium Azide
Constituents: PBS, pH 7.4 -
Concentration information loading... -
PurityAmmonium Sulphate Precipitation
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab16717 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 58 kDa. | |
| IP | Use at an assay dependent dilution. | |
| ICC/IF | Use at an assay dependent dilution. |
Target
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FunctionThe beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
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Tissue specificityExpressed mostly in brain, smooth muscle and ovary.
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Sequence similaritiesBelongs to the calcium channel beta subunit family.
Contains 1 SH3 domain. - Information by UniProt
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Database links
- Entrez Gene: 25297 Rat
- SwissProt: P54287 Rat
- Unigene: 2808 Rat
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Alternative names
- CAB3 antibody
- CACB3_HUMAN antibody
- Cacnb3 antibody
see all
Images
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Western blot - Anti-CAB3 antibody (ab16717)Image from Uriu Y et al, J Biol Chem. 2010 Jul 9;285(28):21750-67. Epub 2010 May 7, Fig 7. DOI 10.1074/jbc.M110.101311PC12 cells transfected with siRNAs were solubilized and analyzed by WB using ab16717.
Protocols
Datasheets and documents
References
This product has been referenced in:
- Uriu Y et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . Read more (PubMed: 20452978) »
