Overview

  • Product name
  • Description
    Rabbit polyclonal to CACNB1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 310-553 of Human CACNB1 (Uniprot ID: Q02641).

  • Positive control
    • 293T, A431, H1299, HeLa, HepG2, MOLT4, Raji and Mouse brain whole cell lysates; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab155179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • Tissue specificity
    Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
  • Sequence similarities
    Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Cellular localization
    Cell membrane > sarcolemma.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAB1 antibody
    • CACB1_HUMAN antibody
    • CACNB1 antibody
    • CACNLB1 antibody
    • Calcium channel L type beta 1 polypeptide antibody
    • Calcium channel voltage dependent beta 1 subunit antibody
    • Calcium channel voltage-dependent subunit beta 1 antibody
    • CCHLB1 antibody
    • Dihydropyridine sensitive L type calcium channel beta 1 subunit antibody
    • MGC41896 antibody
    • Voltage dependent L type calcium channel beta 1 subunit antibody
    • Voltage-dependent L-type calcium channel subunit beta-1 antibody
    see all

Images

  • All lanes : Anti-CACNB1 antibody (ab155179) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : HepG2 whole cell lysate
    Lane 3 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 66 kDa



    7.5% SDS PAGE
  • Anti-CACNB1 antibody (ab155179) at 1/1000 dilution + Mouse brain lysate at 50 µg

    Predicted band size: 66 kDa



    7.5% SDS PAGE
  • Immunofluorescence analysis of methanol-fixed HeLa cells labeling CACNB1 with ab155179 at 1/200 dilution (green). Lower image shows cells co-stained with Hoechst 33342.

References

ab155179 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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