ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Flow cytometric analysis of K562 cells labeling CACNG4 with ab171143 at 1/10 dilution (right histogram) compared to negative control cells (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Western blot - Anti-CACNG4 antibody (ab171143)
Anti-CACNG4 antibody (ab171143) at 1/100 dilution + K562 cell line lysate at 35 µg