Overview

  • Product name

  • Description

    Rabbit polyclonal to cadherin 10
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous levels of total cadherin 10 protein.
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human cadherin 10 (internal sequence).
    Database link: Q9Y6N8

  • Positive control

    • LOVO cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab196662 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/500.

Target

  • Function

    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • Tissue specificity

    Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.
  • Sequence similarities

    Contains 5 cadherin domains.
  • Domain

    Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CAD10_HUMAN antibody
    • Cadherin 10 (T2 cadherin) antibody
    • Cadherin 10 type 2 (T2 cadherin) antibody
    • Cadherin 10 type 2 antibody
    • Cadherin-10 antibody
    • Cadherin10 antibody
    • CDH10 antibody
    • T2 cadherin antibody
    • T2-cadherin antibody
    see all

Images

  • Immunocytochemical analysis of LOVO cells labeling cadherin 10 with ab196662 at a 1/100 dilution. Right image treated with synthesized peptide.

References

ab196662 has not yet been referenced specifically in any publications.

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