Caffeic acid phenethyl ester, ornithine decarboxylase inhibitor (ab143534)

Overview

  • Product name

    Caffeic acid phenethyl ester, ornithine decarboxylase inhibitor
  • Description

    Protein tyrosine kinase and ornithine decarboxylase inhibitor
  • Biological description

    Protein tyrosine kinase and ornithine decarboxylase inhibitor. Caffeic acid (ab120862) derivative. Inhibits 5-lipoxygenase. Induces apoptosis. Modulates cellular redox state. Suppresses MDI-induced adipogenesis. Shows anti-obesity and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    104594-70-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Phenylethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
  • Molecular weight

    284.31
  • Molecular formula

    C17H16O4
  • PubChem identifier

    5281787
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Shin SH  et al. Caffeic Acid Phenethyl Ester, a Major Component of Propolis, Suppresses High Fat Diet-Induced Obesity through Inhibiting Adipogenesis at the Mitotic Clonal Expansion Stage. J Agric Food Chem : (2014). Read more (PubMed: 24611533) »
  • Kinis V  et al. Effects of caffeic acid phenethyl ester on wound healing of nasal mucosa in the rat: an experimental study. Am J Otolaryngol : (2014). Read more (PubMed: 24767474) »
  • Wang LC  et al. The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells. BMC Immunol 10:39 (2009). Read more (PubMed: 19604415) »

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