Calcineurin Autoinhibitory Peptide, calcineurin inhibitor (ab142491)

Overview

  • Product name

    Calcineurin Autoinhibitory Peptide, calcineurin inhibitor
  • Description

    Selective, cell-permeable calcineurin inhibitor
  • Biological description

    Selective, cell-permeable calcineurin inhibitor (IC50 = 10 μM). Inhibits glutamate-mediated neuronal cell death. Immunosuppressant. Active in vitro.
  • Purity

    > 95%
  • CAS Number

    148067-21-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Terada H  et al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem 87:1145-51 (2003). Read more (PubMed: 14622094) »
  • Perrino BA  et al. Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain. J Biol Chem 270:340-6 (1995). Read more (PubMed: 7814394) »
  • Hashimoto Y  et al. Identification of an autoinhibitory domain in calcineurin. J Biol Chem 265:1924-7 (1990). Read more (PubMed: 2153670) »

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