Key features and details
- Rabbit polyclonal to Calcitonin receptor/CT-R
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-Calcitonin receptor/CT-R antibody
See all Calcitonin receptor/CT-R primary antibodies
DescriptionRabbit polyclonal to Calcitonin receptor/CT-R
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Rat
Predicted to work with: Mouse
Synthetic peptide corresponding to Rat Calcitonin receptor/CT-R aa 450 to the C-terminus conjugated to keyhole limpet haemocyanin.
(Peptide available as
- This antibody gave a positive signal in the following tissue lysates: Mouse small intestine; Rat kidney.
Previously labelled as Calcitonin receptor
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab83297 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThis is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family.
Cellular localizationCell membrane.
- Information by UniProt
- Calcitonin receptor antibody
- Calcitonin receptor precursor antibody
- CALCR antibody
All lanes : Anti-Calcitonin receptor/CT-R antibody (ab83297) at 1 µg/ml
Lane 1 : Small Intestine (Mouse) Tissue Lysate
Lane 2 : Kidney (Rat) Tissue Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 60 kDa
Observed band size: 65 kDa why is the actual band size different from the predicted?
Additional bands at: 45 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 5 minutes
Rat Calcitonin receptor precursor has a number of potential glycosylation sites which may affect the migration of the protein (SwissProt data), explaining the bands seen around 65 kDa. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.
ab83297 has been referenced in 1 publication.
- Hughes S et al. Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina. Sci Rep 7:46085 (2017). IHC-Fr ; Mouse . PubMed: 28443635